[root@typhoeus79 c]# more head.c 
#include <stdio.h>
#include <stdlib.h>

typedef struct _point{
    int x;
    int y;
}Point;

Point * InitPoint(int x,int y)
{
    Point *p = (Point *)malloc(sizeof(Point));
    p->x = x;
    p->y = y;

    return p;
}

Point * Incre(Point * p)
{
    p->x = p->x + 1;
    p->y = p->y + 1;

    return p;
}
gcc -fPIC -shared -o libhead.so ./head.c 

[root@typhoeus79 ice_test_m c]# more test.py 
#!/usr/bin/env python2.7
#-*- coding:utf-8 -*-

from ctypes import *

class Point(Structure):
    _fields_ = [("x",c_int),("y",c_int)]

if __name__ == ‘__main__‘:
    ddl = CDLL("./libhead.so")

    ddl.InitPoint.restype = POINTER(Point)

    p = ddl.InitPoint(5,6);


    print p.contents.x
    print p.contents.y
[root@typhoeus79 ice_test_m c]# ./test.py 
5
6