import arcpy, os

aprx = arcpy.mp.ArcGISProject('current')
mv = aprx.activeView

# Change the extent of the map view
ext = mv.camera.getExtent()
ext.XMin = ext.XMin + 100
ext.YMin = ext.YMin + 100
ext.XMax = ext.XMax - 100
ext.YMax = ext.YMax - 100
mv.camera.setExtent(ext)