Ctrl+w，上移
Ctrl+s，下移

AddHandler(Keyboard.KeyDownEvent, (KeyEventHandler)HandleKeyDownEvent);

private void HandleKeyDownEvent(object sender, KeyEventArgs e)
{
    if (e.Key == Key.W && (Keyboard.Modifiers & (ModifierKeys.Control)) == (ModifierKeys.Control))
    {
        if (datagrid.SelectedIndex <= 0)
        {
            datagrid.SelectedIndex = 0;
        }
        else
        {
            datagrid.SelectedIndex = datagrid.SelectedIndex - 1;
        }
    }
    else if (e.Key == Key.S && (Keyboard.Modifiers & (ModifierKeys.Control)) == (ModifierKeys.Control))
    {
        if (datagrid.SelectedIndex == datagrid.Items.Count - 1)
        {
            datagrid.SelectedIndex = datagrid.Items.Count - 1;
        }
        else
        {
            datagrid.SelectedIndex = datagrid.SelectedIndex + 1;
        }
    }
}

wpf 键盘快捷键响应