ubuntu 18IP配置修改/etc/network/interfaces文件不能使其生效，需修改/etc/netplan/下的**.yaml文件。

sudo vi /etc/netplan/01-network-manager-all.yaml

# Let NetworkManager manage all devices on this system
network:
  version: 2
  renderer: NetworkManager
  ethernets:
     enp0s3: #配置的网卡名称,使用ifconfig -a查看得到
       dhcp4: no #dhcp4关闭
       addresses:
             - 172.16.16.199/22
             - 192.168.8.199/24
       #gateway4: 172.16.19.254 #设置网关
       routes:
           - to: 0.0.0.0/0 #路由
             via: 172.16.19.254 #网关
             metric: 100 #优先级
           - to: 0.0.0.0/0 #路由
             via: 192.168.8.254 #网关
             metric: 100 #优先级 
       nameservers:
         addresses: [8.8.8.8]

sudo netplan apply使配置生效

可通过ip addr查看配置的IP