1、创建多实例的目录：
mkdir -p /data/mysql/mysql_3307/{data,tmp,logs}
mkdir -p /data/mysql/mysql_3308/{data,tmp,logs}
2、修改my.cnf的配置文件
vi /data/mysql/mysql_3306/my3306.cnf
#my.cnf
[client]
port = 3306
socket = /data/mysql/mysql_3306/tmp/mysql_3306.sock
[mysql]
prompt=[3306]>
#tee=/data/mysql/mysql_3306/data/query.log
no-auto-rehash
[mysqld]
user = mysql
basedir = /usr/local/mysql
datadir = /data/mysql/mysql_3306/data
port = 3306
socket = /data/mysql/mysql_3306/tmp/mysql_3306.sock
event_scheduler = 0
tmpdir = /data/mysql/mysql_3306/tmp
#timeout
interactive_timeout = 300
wait_timeout = 300
#character set
character-set-server = utf8
#open_files_limit = 65535
max_connections = 100
max_connect_errors = 100000
skip-name-resolve = 1
#logs
log-output=file
slow_query_log = 1
slow_query_log_file = slow.log
log-error = /data/mysql/mysql_3306/data/error.log
log_warnings = 2
pid-file = mysql.pid
long_query_time = 1
#log-slow-admin-statements = 1
#log-queries-not-using-indexes = 1
log-slow-slave-statements = 1
#binlog
binlog_format = mixed
server-id = 203306
log-bin = /data/mysql/mysql_3306/logs/mybinlog
binlog_cache_size = 4M
max_binlog_size = 1G
max_binlog_cache_size = 2G
sync_binlog = 0
expire_logs_days = 10
#relay log
skip_slave_start = 1
max_relay_log_size = 1G
relay_log_purge = 1
relay_log_recovery = 1
log_slave_updates
#slave-skip-errors=1032,1053,1062
explicit_defaults_for_timestamp=1
#buffers & cache
table_open_cache = 2048
table_definition_cache = 2048
table_open_cache = 2048
max_heap_table_size = 96M
sort_buffer_size = 2M
join_buffer_size = 2M
thread_cache_size = 256
query_cache_size = 0
query_cache_type = 0
query_cache_limit = 256K
query_cache_min_res_unit = 512
thread_stack = 192K
tmp_table_size = 96M
key_buffer_size = 8M
read_buffer_size = 2M
read_rnd_buffer_size = 16M
bulk_insert_buffer_size = 32M
#myisam
myisam_sort_buffer_size = 128M
myisam_max_sort_file_size = 10G
myisam_repair_threads = 1
#innodb
innodb_buffer_pool_size = 100M
innodb_buffer_pool_instances = 1
innodb_data_file_path = ibdata1:1G:autoextend
innodb_flush_log_at_trx_commit = 2
innodb_log_buffer_size = 64M
innodb_log_file_size = 256M
innodb_log_files_in_group = 3
innodb_max_dirty_pages_pct = 50
innodb_file_per_table = 1
innodb_rollback_on_timeout
innodb_status_file = 1
innodb_io_capacity = 2000
transaction_isolation = READ-COMMITTED
innodb_flush_method = O_DIRECT
[mysqld_safe]
open_file_limit = 65535
3、复制配置文件到其他实例的目录：
cp /data/mysql/mysql_3306/my3306.cnf /data/mysql/mysql_3307/my3307.cnf
cp /data/mysql/mysql_3306/my3306.cnf /data/mysql/mysql_3308/my3308.cnf
4、修改其他实例的目录路径
vi /data/mysql/mysql_3307/my3307.cnf
:%s/3306/3307/g
vi /data/mysql/mysql_3308/my3308.cnf
:%s/3306/3308/g
5、赋予权限：
chown -R mysql:mysql /usr/local/mysql
chown -R mysql:mysql /data
chown -R mysql:mysql /opt/mysql
6、多实例的初始化：
cd /usr/local/mysql
./scripts/mysql_install_db --user=mysql --datadir=/data/mysql/mysql_3306/data --defaults-file=/data/mysql/mysql_3306/my3306.cnf
./scripts/mysql_install_db --user=mysql --datadir=/data/mysql/mysql_3307/data --defaults-file=/data/mysql/mysql_3307/my3307.cnf
./scripts/mysql_install_db --user=mysql --datadir=/data/mysql/mysql_3308/data --defaults-file=/data/mysql/mysql_3308/my3308.cnf
7、启动进程：
/usr/local/mysql/bin/mysqld_safe --defaults-file=/data/mysql/mysql_3306/my3306.cnf &
/usr/local/mysql/bin/mysqld_safe --defaults-file=/data/mysql/mysql_3307/my3307.cnf &
/usr/local/mysql/bin/mysqld_safe --defaults-file=/data/mysql/mysql_3308/my3308.cnf &
8、查看指定文件目录是否存在：（每个实例在启动前都要查看）
ll /data/mysql/mysql_3306/tmp
srwxrwxrwx 1 mysql mysql 0 Dec 18 07:08 mysql_3306.sock
ll /data/mysql/mysql_3307/tmp
srwxrwxrwx 1 mysql mysql 0 Dec 18 07:10 mysql_3307.sock
ll /data/mysql/mysql_3308/tmp
srwxrwxrwx 1 mysql mysql 0 Dec 18 07:22 mysql_3308.sock
9、多实例的登陆方式：
mysql --protocol=tcp -h 127.0.0.1 -uroot -P3306 --socket=/data/mysql/mysql_3306/tmp/mysql_3306.sock
mysql --protocol=tcp -h 127.0.0.1 -uroot -P3307 --socket=/data/mysql/mysql_3307/tmp/mysql_3307.sock
mysql --protocol=tcp -h 127.0.0.1 -uroot -P3308 --socket=/data/mysql/mysql_3308/tmp/mysql_3308.sock
10、关闭mysql：
mysqladmin -S /data/mysql/mysql_3308/tmp/mysql_3306.sock shutdown
mysqladmin -S /data/mysql/mysql_3308/tmp/mysql_3307.sock shutdown
mysqladmin -S /data/mysql/mysql_3308/tmp/mysql_3308.sock shutdown
http://www.cnblogs.com/abobo/p/4172760.html