今天总算解决了困扰我快一周的问题。

This application failed to start because no Qt platform plugin could be initialized. Reinstalling the application may fix this problem.

尝试了许多解决方法，*上有许多回答，包括copy plugin、环境变量…

Qt creator fails to open on Windows 10 “no Qt platform plugin could be initialized” - Stack Overflow

下面总结了遇到该问题的诸多教程，可一一尝试。

plugin复制/缺少dll：

• 程序运行时提示This application failed to start because no Qt platform plugin could be initialized.

• How To Fix No Qt Platform Plugin Could Be Initialized Error - This Application Failed To Start

• PyQt：解决This application failed to start because no Qt platform plugin could be initialized问题 - 程序员大本营 (pianshen.com)

• Qt Designer启动显示This application failed to start because no Qt platform plugin could be initializedin

• this application failed to start because no qt platform plugin could be initialized

环境变量：

• 解决designer运行报错:This application failed to start because no Qt platform plugin could be initialized问题

• Designer——运行报错:This application failed to start because no Qt platform plugin could be initialized_Williamcsj的博客-CSDN博客

• 解决This application failed to start because no Qt platform plugin could be initialized问题_种言和的白菜的博客-CSDN博客

中文路径：

• 解决QT5移植报错：This application failed to start because no Qt platform plugin could be initialized (shuzhiduo.com)

我记得我差不多全试了一遍，但还是没有解决，我一直是觉得我系统安装的Qt和anaconda中的Qt冲突，后来发现VS2017运行Qt是可以的，就是python中无法运行，所以又开始重新一轮的尝试，毕竟不想换电脑。

终于在把环境变量删除后，重装了Qt、pyqt5后解决了，就是这么玄乎。

pip install pyqt5
pip install qt==5.9.7

所以大家可以一一尝试，重装、plugin、环境变量都可以试一下，不要气馁。